5F-AKB48
| 5F-AKB48 | |||||||||||||||||||||||||||||||
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| Chemical Nomenclature | |||||||||||||||||||||||||||||||
| Common names | 5F-AKB48, 5F-APINACA | ||||||||||||||||||||||||||||||
| Substitutive name | 5F-APINACA | ||||||||||||||||||||||||||||||
| Systematic name | N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide | ||||||||||||||||||||||||||||||
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| Psychoactive class | Cannabinoid | ||||||||||||||||||||||||||||||
| Chemical class | Indazolecarboxamide / Adamantane | ||||||||||||||||||||||||||||||
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Chemistry
Pharmacology
Although this substance has not been formally studied from analysis of the structure, it is presumed that AB-FUBINACA has a similar binding profile to that of other cannibanoids and matches many of the in vivo properties of Δ9-THC. As with the compounds within cannabis, AB-FUBINACA exhibits its range of effects via full agonism of both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2.
Subjective effects
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This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it. |
The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.
Physical effects
- Spontaneous tactile sensations - The body high of AB-FUBINACA can be described as a warm and soft pleasurable, all-encompassing tingling sensation that spreads over the body prior to initial ingestion. It maintains a consistent presence that quickly rises with the onset and hits its limit once the peak has been reached before immediately dissipating.
- Sedation - Generally, the effects on the user's energy levels are primarily sedating. This encourages one to relax, and at higher doses fall asleep. This can however be suppressed by simply forcing oneself to engage in physical activities.
- Motor control loss - This substance causes a partial to moderate suppression of motor control which intensifies proportional to dosage but rarely results in a complete inability to walk and perform basic movements.
- Appetite stimulation - As with many other cannabinoids, AB-FUBINACA causes an increase in appetite[1], known colloquially as "the munchies" in popular American and United Kingdom culture. Clinical studies and survey data have found that cannabis increases food enjoyment and interest in food.[2] This is thought to be due to the way in which endocannabinoids in the hypothalamus activate cannabinoid receptor that are responsible for maintaining food intake.[3]
- Dehydration
- Vasodilation
- Pain relief - Cannabinoids have been clinically demonstrated to provide pain relief via agonism of cannabinoid receptors CB1 and CB2, which extends to synthetic cannabinoid receptor agonists. [4][5]
- Increased bodily weight or Decreased bodily weight
- Changes in gravity
Cognitive effects
- Current mind state enhancement
- Thought connectivity
- Thought deceleration
- Conceptual thinking
- Mindfulness
- Information processing suppression
- Dream suppression
- Anxiety
- Paranoia
Auditory effects
Toxicity and Harm Potential
Since AB-FUBINACA is a relatively new substance, there is very little data available about its toxicity or addiction potential. Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to fall asleep.
As the material is active in the milligram range, it is important to remain vigilant when dosing as to avoid a negative experience.
Legal Issues
See Also
References
- ↑ Mechoulam, R. (1984). Cannabinoids as therapeutic agents. Boca Raton, FL: CRC Press. ISBN 0-8493-5772-1.
- ↑ How Marijuana Works | http://science.howstuffworks.com/marijuana4.htm
- ↑ How Marijuana Works | http://science.howstuffworks.com/marijuana4.htm
- ↑ http://onlinelibrary.wiley.com/doi/10.1111/j.1526-4637.2009.00703.x/abstract
- ↑ Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials | http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2011.03970.x/abstract