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4-HO-MPT

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4-HO-MPT
Chemical Nomenclature
Common names 4-HO-MPT, Meprocin
Substitutive name 4-hydroxy-N-methyl-N-propyltryptamine
Systematic name 3-[2-(Methylpropylamino)ethyl]-4-indolol
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



⇣ Oral
Dosage
Threshold 5 mg
Light 10 - 20 mg
Common 20 - 30 mg
Strong 30 - 50 mg
Heavy 50 mg +
Duration
Total 5 - 7 hours
Onset 20 - 60 minutes
Come up 1 - 2 hours
Peak 2 - 3 hours
Offset 1 - 2 hours
After effects 2 - 12 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions
Summary sheet: 4-HO-MPT

4-Hydroxy-N-methyl-N-propyltryptamine (also known as 4-HO-MPT) is a novel and obscure hallucinogenic psychedelic substance of the tryptamine class and can be considered to be homologous to 4-HO-DMT (i.e. Psilocin) and other hallucinogenic tryptamines with powerful psychedelic effects, yet with its own unique style variations.

Little is currently known about this substance due to its limited history of use, though it is starting to gain interest within the psychonaut community who seek out these types of experiences, being a similar but at the same time distinct variation on the mushroom or psilocin experience.[1]

Today 4-HO-MPT is either used rarely as a recreational drug or as entheogenic compound and is typically acquired through the use of online research chemical vendors on which it first appeared as recently as mid 2016.

Chemistry

4-HO-MPT, or 4-hydroxy-N,N-methylpropyltryptamine, is a synthetic indole molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-HO-MPT is substituted at R4 of its indole heterocycle with a hydroxyl functional group OH−. It also contains a propyl and ethyl chain bound to the terminal amine RN of its tryptamine backbone (MPT).

Pharmacology

Main article: Serotonergic psychedelic

Like with most psychedelic tryptamines, 4-HO-EPT is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 4-HO-EPT's binding efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

 This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Cognitive effects

Visual effects

Enhancements

Distortions

Geometry

Hallucinatory states

Auditory effects

Toxicity and harm potential

Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational 4-HO-MPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 4-HO-MPT is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 4-HO-MPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

4-HO-MPT is generally considered not habit-forming and the desire to use it can actually decrease with regular consumption. Like with most psychedelics, it is most often thought to be self-regulating.

Tolerance to the effects of 4-HO-MPT are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 4-HO-MPT presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 4-HO-MPT all psychedelics will have a reduced effect.

Due to its relative obscurity, the possession and sale of 4-HO-MPT is unscheduled in most countries.

  • United Kingdom: It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[2]
  • United States: 4-HO-MPT is unscheduled in the United States. It may be considered an analog of psilocin (which is a Schedule I drug under the Controlled Substances Act). As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analog Act.

See also

References

  1. ↑ http://www.bluelight.org/vb/members/377522-Kaleida%7CView Profile: Kaleida | Bluelight
  2. ↑ Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted


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