This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Itchiness
Itchiness is the sensation that causes a person the desire or reflex to scratch at their skin. Drugs, such as opioids, that activate histamine receptors or trigger histamine release can cause this effect. A way to counteract the itchiness in cases of substance use is to take an anti-histamine such as DPH.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- Acetylfentanyl
- Buprenorphine
- Cocoa
- Codeine
- Desomorphine
- Dextromethorphan
- Dextropropoxyphene
- Dihydrocodeine
- Diphenhydramine
- Ethylmorphine
- Fentanyl
- Heroin
- Hydrocodone
- Hydromorphone
- Kratom
- Methadone
- Morphine
- N-Acetylcysteine
- O-Desmethyltramadol
- Oxycodone
- Oxymorphone
- Pethidine
- Tapentadol
- Tianeptine
- Tramadol
- U-47700