Substituted morphinans

General formula of morphinan molecule.

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Morphinans are a class of chemicals that include compounds with psychoactive effects.

Chemistry

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Morphinans are made up of the morphinan molecule with altering functional groups attached on the numbered carbons.

Pharmacology

The morphinans are a large chemical class and compounds within it have differing pharmacological effects. These include action upon the NMDA receptor, the μ-opioid receptor and the σ1 and σ2 sigma receptors.

Examples

Morphinans are seen throughout organic chemistry including many analgesic, antitussive and anaesthetic compounds.

Dissociative drugs

• DXM

Analgesic drugs

• Levomethorphan
• Phenomorphan
• Nalbuphine

See also

• Dissociatives
• Arylcyclohexylamines

References

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