Antipsychotic: Difference between revisions
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'''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>http://books.google.ca/books?id=Q4hG2gRhy7oC&pg=PA151</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[Delusions|delusions]], hallucinations, or disordered thought), particularly in | '''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>http://books.google.ca/books?id=Q4hG2gRhy7oC&pg=PA151</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[Delusions|delusions]], [[hallucinations]], or [[thought disorganization|disordered thought]]), particularly in schizophrenia and bipolar disorder. | ||
First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, called atypical antipsychotics, have been developed more recently. The first atypical antipsychotic, [[clozapine]], was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's [[dopamine]] pathways but atypicals tend to act on [[serotonin]] receptors as well. | First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, called atypical antipsychotics, have been developed more recently. The first atypical antipsychotic, [[clozapine]], was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's [[dopamine]] pathways but atypicals tend to act on [[serotonin]] receptors as well. | ||
Notable and relatively common adverse effects of antipsychotics include extrapyramidal symptoms (which involve motor control), hyperprolactinaemia (primarily in typicals), weight gain and metabolic abnormalities (mostly in atypicals).<ref name = "SCZ">{{cite web | url = http://emedicine.medscape.com/article/288259-overview | title = Schizophrenia | author = Frankenburg FR, Dunayevich E, Albucher RC, Talavera F | publisher = emedicine.medscape.com | accessdate = 2013-10-02 }}</ref> | Notable and relatively common adverse effects of antipsychotics include extrapyramidal symptoms (which involve motor control), hyperprolactinaemia (primarily in typicals), weight gain and metabolic abnormalities (mostly in atypicals).<ref name = "SCZ">{{cite web | url = http://emedicine.medscape.com/article/288259-overview | title = Schizophrenia | author = Frankenburg FR, Dunayevich E, Albucher RC, Talavera F | publisher = emedicine.medscape.com | accessdate = 2013-10-02 }}</ref> | ||
===Examples=== | |||
===See also=== | ===See also=== | ||
Revision as of 06:53, 28 September 2016
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Antipsychotics (also known as neuroleptics or major tranquilizers)[1] are a class of psychiatric medication primarily used to manage psychosis (including delusions, hallucinations, or disordered thought), particularly in schizophrenia and bipolar disorder.
First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, called atypical antipsychotics, have been developed more recently. The first atypical antipsychotic, clozapine, was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's dopamine pathways but atypicals tend to act on serotonin receptors as well.
Notable and relatively common adverse effects of antipsychotics include extrapyramidal symptoms (which involve motor control), hyperprolactinaemia (primarily in typicals), weight gain and metabolic abnormalities (mostly in atypicals).[2]
Examples
See also
References
- ↑ http://books.google.ca/books?id=Q4hG2gRhy7oC&pg=PA151
- ↑ Frankenburg FR, Dunayevich E, Albucher RC, Talavera F. "Schizophrenia". emedicine.medscape.com. Retrieved 2013-10-02.