Phencyclidines

Structure of phencyclidine

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Phencyclidines refers to a class of compounds which typically produce dissociative anaesthesia.

Examples

• 3-MeO-PCMo
• 3-MeO-PCE
• 3-MeO-PCP
• 4-MeO-PCP
• Ketamine
• Methoxetamine (MXE)
• Methoxyketamine
• Phencyclidine (PCP)

Toxicity and Harm Potential

Psychosis

There are numerous reports in the medical literature and throughout online forums, which have identified an increased risk of developing psychotic symptoms when using phencyclidines, arylcyclohexylamines and other NMDA antagonists.

This risk appears to be increased when other substances such as psychedelics, stimulants, and deliriants are combined; and when the drug is used habitually over the course of several days.

Because of this, it is advised that the use of phencyclidines should be kept to a respectable minimum, and that combinations should only be explored by experienced travellers who have carefully and steadily increased their dose over time, fully understand and are prepared for the risks. As always, a sitter is recommended when exploring any new substance or dosage.

Phencyclidines appear to cause trouble more reliably than other NMDA antagonists, likely because of its structural piperidine ring, and because of their potency and duration.

References

Substance	Source	Circumstance (total dose / duration)	Consequences
PCP	Bluelight thread title	1 gram over 3 days	Shit got fucked up
etc	etc	etc	etc

See also

• Arylcyclohexylamine (Wikipedia)
• Dissociative
• Ketamine
• Methoxetamine
• NMDA receptor antagonist