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Revision as of 07:22, 16 September 2016

Tapering refers to the gradual lowering of a drug's dosage over a prolonged period of time. It is a harm reduction practice which is highly recommended for those who are physically dependent on psychoactive substances because stopping one's extended usage abruptly (also known as going "cold turkey") can result in unpleasant withdrawal symptoms, which can sometimes be life-threatening.[1] It is important to note that the sudden discontinuation of alcohol, benzodiazepines, and barbiturates can result in seizures and death.[2]

Withdrawal symptoms may occur after ceasing usage abruptly following a few weeks or longer of steady dosing and the severity of the withdrawal symptoms increase the longer one uses the substance. Withdrawal symptoms can generally be minimized or avoided by tapering the dose slowly and carefully monitoring for symptoms. Symptoms vary depending on the specific substance and can include (but are not limited to) increased heart rate and/or blood pressure, irritability, anxiety, nausea, headaches, tremors, insomnia, depression, sensitivity to pain, hallucinations, seizures, and death.

See also

References

  1. Canadian Guideline for Safe and Effective Use of Opioids for Chronic Non-Cancer Pain - Appendix B-6: Benzodiazepine Tapering | http://nationalpaincentre.mcmaster.ca/opioid/cgop_b_app_b06.html
  2. A fatal case of benzodiazepine withdrawal. (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/19465812