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Revision as of 09:58, 2 September 2016

Tapering refers to the gradual lowering of a drug's dosage over a prolonged period of time. It is a harm reduction practice which is highly recommended for those who are physically dependent on psychoactive substances because stopping one's extended usage abruptly will result in withdrawal symptoms, which can sometimes be life-threatening (in the case of benzodiazepines).[1]

Withdrawal symptoms may occur after ceasing usage abruptly following a few weeks or longer of steady dosing and the severity of the withdrawal symptoms increase the longer one uses the substance. Symptoms vary depending on the substance and can include (but are not limited to) irritability, anxiety, nausea, headaches, tremors, insomnia, depression, sensitivity to pain, hallucinations, seizures, and death.

It is important to note that the sudden discontinuation of benzodiazepines is especially dangerous, sometimes resulting in seizures or death.[2]

See also

References

  1. Canadian Guideline for Safe and Effective Use of Opioids for Chronic Non-Cancer Pain - Appendix B-6: Benzodiazepine Tapering | http://nationalpaincentre.mcmaster.ca/opioid/cgop_b_app_b06.html
  2. A fatal case of benzodiazepine withdrawal. (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/19465812

For more information on tapering from benzodiazepines in a controlled manner, please see this guide.