Substituted morphinans

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General formula of morphinan molecule.

Morphinans are a class of chemicals that include compounds with psychoactive effects.

Chemistry

Morphinans are made up of the morphinan molecule, with altering functional groups attached on the numbered carbons.

Pharmacology

The morphinans are a large chemical class and compounds within it have differing pharmacological effects. These include action upon the NMDA receptor, the μ-opioid receptor and the σ1 and σ2 sigma receptors.

Examples

Morphinans are seen throughout organic chemistry, including many analgesic, antitussive and anaesthetic compounds.

Dissociative Drugs

• DXM

Analgesic Drugs

• Levomethorphan
• Phenomorphan
• Nalbuphine

See Also

• Dissociatives
• Arylcyclohexylamines