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Template:Peganum harmala alkaloids: Difference between revisions
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>David Hedlund Creating Template:Peganum harmala alkaloids |
>David Hedlund ttps://www.cdfa.ca.gov/plant/ipc/encycloweedia/weedinfo/peganum.htm |
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! [[Harmine]] (banisterine, telepathine) | ! [[Harmine]] (banisterine, telepathine) | ||
| 0.44%<ref name=chroma>{{cite journal |vauthors=Pulpati H, Biradar YS, Rajani M |title=High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala |journal=J AOAC Int |volume=91 |issue=5 |pages=1179–85 |year=2008 |doi=10.1093/jaoac/91.5.1179 |pmid=18980138|doi-access=free }}</ref>–1.84%<ref name=partial/>–4.3%<ref name=new1>{{cite journal |vauthors=Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H |title=beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO) |journal=Food Chem. Toxicol. |volume=48 |issue=3 |pages=839–45 |date=March 2010 |pmid=20036304 |doi=10.1016/j.fct.2009.12.019}}</ref> – The coatings of the seeds are said to contain large amounts of harmine.<ref name=cdfa/> | | 0.44%<ref name=chroma>{{cite journal |vauthors=Pulpati H, Biradar YS, Rajani M |title=High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala |journal=J AOAC Int |volume=91 |issue=5 |pages=1179–85 |year=2008 |doi=10.1093/jaoac/91.5.1179 |pmid=18980138|doi-access=free }}</ref>–1.84%<ref name=partial/>–4.3%<ref name=new1>{{cite journal |vauthors=Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H |title=beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO) |journal=Food Chem. Toxicol. |volume=48 |issue=3 |pages=839–45 |date=March 2010 |pmid=20036304 |doi=10.1016/j.fct.2009.12.019}}</ref> – The coatings of the seeds are said to contain large amounts of harmine.<ref name=cdfa>{{cite web|url= https://www.cdfa.ca.gov/plant/ipc/encycloweedia/weedinfo/peganum.htm |title=''African rue or Harmel'' |access-date=17 February 2021 |publisher=cdfa.ca.gov |archive-url=https://web.archive.org/web/20151022101427/https://www.cdfa.ca.gov/plant/ipc/encycloweedia/weedinfo/peganum.htm |archive-date=22 October 2015 }}</ref> | ||
| [[Reversible inhibitor of monoamine oxidase A]] (RIMA) | | [[Reversible inhibitor of monoamine oxidase A]] (RIMA) | ||
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Revision as of 02:06, 16 July 2021
| Alkaloid | Content | Type |
|---|---|---|
| Desoxypeganine[1] | MAO-A[2] | |
| Harmalicidine[3] | ||
| Harmaline (harmidine) | 0.25%[4]–0.79%[5]–5.6%[6] | Reversible inhibitor of monoamine oxidase A (RIMA) |
| Harmalol | 0.6%[6]–3.90%[4] | |
| Harmane (harman) | 0.16%[4] | MAO-A and MAO B[7] |
| Harmine (banisterine, telepathine) | 0.44%[5]–1.84%[4]–4.3%[6] – The coatings of the seeds are said to contain large amounts of harmine.[8] | Reversible inhibitor of monoamine oxidase A (RIMA) |
| Tetrahydroharmine (THH) | 0.1%[6] | Serotonine reuptake inhibitor[9] |
| Vasicine (peganine)[10] | 0.25%[5] | |
| Vasicinone[10] | 0.0007%[5] |
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841998/
- ↑ Algorta, J; Pena, MA; Maraschiello, C; Alvarez-González, A; Maruhn, D; Windisch, M; Mucke, HA (March 2008). "Phase I clinical trial with desoxypeganine, a new cholinesterase and selective MAO-A inhibitor: tolerance and pharmacokinetics study of escalating single oral doses". Methods and findings in experimental and clinical pharmacology. 30 (2): 141–7. doi:10.1358/mf.2008.30.2.1159649. PMID 18560630.
- ↑ Lamchouri, F; Zemzami, M; Jossang, A; Abdellatif, A; Israili, ZH; Lyoussi, B (July 2013). "Cytotoxicity of alkaloids isolated from Peganum harmala seeds". Pakistan journal of pharmaceutical sciences. 26 (4): 699–706. PMID 23811445.
- ↑ 4.0 4.1 4.2 4.3 Hemmateenejad B, Abbaspour A, Maghami H, Miri R, Panjehshahin MR (August 2006). "Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts". Anal. Chim. Acta. 575 (2): 290–9. doi:10.1016/j.aca.2006.05.093. PMID 17723604.
- ↑ 5.0 5.1 5.2 5.3 Pulpati H, Biradar YS, Rajani M (2008). "High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala". J AOAC Int. 91 (5): 1179–85. doi:10.1093/jaoac/91.5.1179
. PMID 18980138.
- ↑ 6.0 6.1 6.2 6.3 Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H (March 2010). "beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO)". Food Chem. Toxicol. 48 (3): 839–45. doi:10.1016/j.fct.2009.12.019. PMID 20036304.
- ↑ Herraiz, T; Chaparro, C (18 January 2006). "Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee". Life sciences. 78 (8): 795–802. doi:10.1016/j.lfs.2005.05.074. PMID 16139309.
- ↑ "African rue or Harmel". cdfa.ca.gov. Archived from the original on 22 October 2015. Retrieved 17 February 2021.
- ↑ Callaway, James C.; McKenna, Dennis; Grob, Charles S.; et al. (June 1999). "Pharmacokinetics of hoasca alkaloids in healthy humans". Journal of Ethnopharmacology. 65 (3): 243–56. doi:10.1016/S0378-8741(98)00168-8. ISSN 0279-1072. PMID 10404423.
- ↑ 10.0 10.1 Cite error: Invalid
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