Increased perspiration

Increased perspiration, or hyperhidrosis, is the condition characterized by abnormally increased sweating, in excess of that required for regulation of body temperature. The term diaphoresis is also used, and is essentially synonymous. Diaphoresis, however, is quite commonly used when extremely low blood pressure (shock) is also present. Consequently, the term diaphoresis is sometimes defined as "sweat shock syndrome". All terms refer to an abnormally large increase in sweating, regardless of the cause.

Hyperhidrosis is a symptom of sympathetic arousal, the "fight-or-flight" response, and is a common effect of stimulant drugs. Any psychoactive drug which exerts strong serotonergic, dopaminergic, or adrenergic effects may cause hyperhidrosis. Cholinergics and, to a lesser extent, opioids have also been implicated.^{[citation needed]}

Psychoactive substances Compounds within our psychoactive substance index which may cause this effect include:

• 2-Aminoindane
• Amphetamine
• Cocaine
• Ethylphenidate
• MDMA
• Mephedrone
• Methylone
• Methylphenidate

References: 1. http://www.jbc.org/content/99/3/781.full.pdf 2