Template:DangerousInteractions/SerotoninSyndrome: Difference between revisions

Revision as of 21:06, 8 August 2018

Combinations with the following substances can increase the amount of serotonin in the brain to dangerous, possibly fatal, levels.

MAOIs such as syrian rue, banisteriopsis caapi, 2C-T-2, 2C-T-7, αMT, and some antidepressants^[1]
Serotonin releasers such as MDMA, 4-FA, methylone and αMT
Selective serotonin re-uptake inhibitors (SSRIs)
Serotonin-norepinephrine reuptake inhibitors (SNRIs) such as tramadol and DXM
5-HTP

↑ Gillman, P. K. (2005). Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. British Journal of Anaesthesia, 95(4), 434-441. https://doi.org/10.1093/bja/aei210

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-Combinations with the following substances can dangerously increase [[serotonin]] levels in the brain. Serotonin syndrome can be fatal if left untreated.
+Combinations with the following substances can increase the amount of [[serotonin]] in the brain to dangerous, possibly fatal, levels.
 *'''[[DangerousInteraction::MAOIs]]''' such as '''[[syrian rue]]''', '''[[banisteriopsis caapi]]''', '''[[2C-T-2]]''', '''[[2C-T-7]]''', '''[[αMT]]''', and some [[antidepressant]]s<ref>Gillman, P. K. (2005). Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. British Journal of Anaesthesia, 95(4), 434-441. https://doi.org/10.1093/bja/aei210</ref>
 *'''[[DangerousInteraction::Serotonin releasers]]''' such as '''[[MDMA]]''', '''[[4-FA]]''', '''[[methylone]]''' and '''[[αMT]]'''