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Antihistamine: Difference between revisions

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>David Hedlund
==External links== *Antihistamine (Wikipedia)
>Unity
Wording and formatting. Added Literature section.
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{{stub}}
{{stub}}
[[File:Histamine.svg|200px|thumbnail|The structure of Histamine]]
[[File:Histamine.svg|200px|thumbnail|The structure of Histamine]]
An '''anti-histamine''' (commonly called a '''histamine antagonist''') is a pharmaceutical drug that inhibits the action of [[histamine]] by either blocking its attachment to histamine [[receptor]]s or inhibiting the enzymatic activity of histidine decarboxylase which catalyzes the transformation of [[histidine]] into histamine. Anti-histamines are commonly used for the relief of allergies<ref>Sicherer, Scott H. M.D., Understanding and Managing Your Child's Food Allergy. Baltimore: The Johns Hopkins University Press, 2006 ISBN 0-8018-8492-6.</ref> and sometimes for their [[subjective effects index|psychoactive effects]].
'''Antihistamines''' are pharmaceutical drugs that inhibits the action of [[histamine]] by either blocking its attachment to histamine [[receptor]]s or inhibiting the enzymatic activity of histidine decarboxylase which catalyzes the transformation of [[histidine]] into histamine. Anti-histamines are commonly used for the relief of allergies<ref>Sicherer, Scott H. M.D., Understanding and Managing Your Child's Food Allergy. Baltimore: The Johns Hopkins University Press, 2006 ISBN 0-8018-8492-6.</ref> and sometimes for their [[subjective effects index|psychoactive effects]].


==Pharmacology==
==Pharmacology==
{{pharmacology}}
{{pharmacology}}
Most anti-histamines have [[Agonist#Agonists|inverse agonistic]] effects upon histamine receptors.
Most antihistamines have [[Agonist#Agonists|inverse agonistic]] effects upon histamine receptors.


==Examples==
==Examples==
Anti-histamines are seen throughout organic chemistry including psychoactive and anti-allergenic compounds.
Antihistamines are seen throughout organic chemistry including psychoactive and anti-allergenic compounds.


*[[Diphenhydramine]]
*[[Diphenhydramine]]
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==External links==
==External links==
*[[wikipedia:Antihistamine|Antihistamine (Wikipedia)]]
*[[wikipedia:Antihistamine|Antihistamine (Wikipedia)]]
==Literature==
*Emanuel, M. B. (1999). Histamine and the antiallergic antihistamines: a history of their discoveries. Clinical & Experimental Allergy, 29(S3), 1-11. https://doi.org/10.1046/j.1365-2222.1999.00004.x-i1


==References==
==References==

Revision as of 00:53, 3 July 2018

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

The structure of Histamine

Antihistamines are pharmaceutical drugs that inhibits the action of histamine by either blocking its attachment to histamine receptors or inhibiting the enzymatic activity of histidine decarboxylase which catalyzes the transformation of histidine into histamine. Anti-histamines are commonly used for the relief of allergies[1] and sometimes for their psychoactive effects.

Pharmacology

This pharmacology section is incomplete.

You can help by adding to it.

Most antihistamines have inverse agonistic effects upon histamine receptors.

Examples

Antihistamines are seen throughout organic chemistry including psychoactive and anti-allergenic compounds.

See also

Literature

References

  1. Sicherer, Scott H. M.D., Understanding and Managing Your Child's Food Allergy. Baltimore: The Johns Hopkins University Press, 2006 ISBN 0-8018-8492-6.