Warning
This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.

Itchiness: Difference between revisions

From PsychonautWiki Archive
Jump to navigation Jump to search
>Graham
Reference
>Josikins
overhauling effect components as part of my SEI improvement project
Line 1: Line 1:
<onlyinclude>
<onlyinclude>
'''Itchiness''' is the sensation that causes a person the desire or reflex to scratch at their skin. Substances such as [[opioids]],<ref>Walsh, S. L., Strain, E. C., Abreu, M. E., & Bigelow, G. E. (2001). Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans. Psychopharmacology, 157(2), 151-162. https://doi.org/10.1007/s002130100788</ref> that activate [[histamine]] receptors or trigger histamine release can cause this effect. A way to counteract the itchiness in cases of substance use is to take an [[antihistamine]] such as [[DPH]] ('''Diphenhydramine''').
'''Itchiness''' is the sensation that causes a person the desire or reflex to scratch at their skin. At lower levels, itchiness can occur as a subtle and minor annoyance which is easy to ignore. However, at higher levels, itchiness can become so intense that is incredibly uncomfortable and can even result in the person damaging their skin through repetitive scratching motions.
 
Itchiness is most commonly induced under the influence of [[dosage#heavy|heavy]] [[dosage|dosages]] of [[opioid]] compounds, such as [[heroin]], [[fentanyl]], [[tramadol]], and [[kratom]]. This is due to the way in which opioids activate [[histamine]] receptors and trigger histamine release. An effective technique for counteracting itchiness in cases of substance use is to take an [[antihistamine]] such as [[DPH]] (Diphenhydramine).
</onlyinclude>
</onlyinclude>
===Psychoactive substances===
===Psychoactive substances===

Revision as of 23:22, 17 March 2018

Itchiness is the sensation that causes a person the desire or reflex to scratch at their skin. At lower levels, itchiness can occur as a subtle and minor annoyance which is easy to ignore. However, at higher levels, itchiness can become so intense that is incredibly uncomfortable and can even result in the person damaging their skin through repetitive scratching motions.

Itchiness is most commonly induced under the influence of heavy dosages of opioid compounds, such as heroin, fentanyl, tramadol, and kratom. This is due to the way in which opioids activate histamine receptors and trigger histamine release. An effective technique for counteracting itchiness in cases of substance use is to take an antihistamine such as DPH (Diphenhydramine).

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

See also