Warning
This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.

Abnormal heartbeat: Difference between revisions

From PsychonautWiki Archive
Jump to navigation Jump to search
← Older editNewer edit →
>David Hedlund
remove my line breaks
>Josikins
overhauling effect components as part of my SEI improvement project (still needs more work)
Line 1: Line 1:
<onlyinclude>
<onlyinclude>
An '''abnormal heartbeat''' (also called an '''arrhythmia''' or '''dysrhythmia''') is any of a group of conditions in which the electrical activity of the heart is irregular.  
An '''abnormal heartbeat''' (also called an '''arrhythmia''' or '''dysrhythmia''') is any of a group of conditions in which the electrical activity of the heart is irregular. During this state, the heartbeat may be too fast (over 100 beats per minute) or too slow (less than 60 beats per minute) and may be regular or irregular. A heartbeat that is too fast is called tachycardia, and a heartbeat that is too slow is called bradycardia. Although many arrhythmias are not life-threatening, it is worth noting that some can cause cardiac arrest in extreme cases.


The heartbeat may be too fast (over 100 beats per minute) or too slow (less than 60 beats per minute) and may be regular or irregular. A heartbeat that is too fast is called tachycardia, and a heartbeat that is too slow is called bradycardia. Although many arrhythmias are not life-threatening, some can cause cardiac arrest.
An abnormal heartbeat is most commonly induced under the influence of [[dosage#common|moderate]] [[dosage|dosages]] of a [[stimulants]] and [[depressants]] compounds, such as [[cocaine]],<ref>O’Leary, Michael E, and Jules C Hancox. “Role of Voltage-Gated Sodium, Potassium and Calcium Channels in the Development of Cocaine-Associated Cardiac Arrhythmias.” British Journal of Clinical Pharmacology 69.5 (2010): 427–442. PMC. Web. 27 June 2017.</ref> [[methamphetamine]], and [[GABAergic]]s. While [[stimulant]]s tend to increase a person's heart rate, [[depressants]] tend to decrease it. Combining the two can often result in dangerously irregular heartbeats.
 
Much like class 1b antiarrhythmics, [[cocaine]] is well known to be a voltage-gated sodium ion channel blocker, which may cause potentially fatal arrhythmias such as ventricular tachycardias and QT interval elongation at higher doses.<ref>O’Leary, Michael E, and Jules C Hancox. “Role of Voltage-Gated Sodium, Potassium and Calcium Channels in the Development of Cocaine-Associated Cardiac Arrhythmias.” British Journal of Clinical Pharmacology 69.5 (2010): 427–442. PMC. Web. 27 June 2017.</ref> Parasympatholytics such as [[atropine]] block the vagal effects of [[acetylcholine]] on the sinoatrial node, often resulting in sinus [[tachycardia]], hence atropine is often used clinically for symptomatic [[Decreased heart rate|bradycardia]].{{citation needed}}
 
In the context of substance usage, many compounds alter one's heartrate. For example, [[stimulant]]s tend to increase one's heart rate whilst [[depressants]] tend to decrease it. Combining the two can often result in dangerously irregular heartbeats.
</onlyinclude>
</onlyinclude>
===Psychoactive substances===
===Psychoactive substances===

Revision as of 20:03, 15 March 2018

An abnormal heartbeat (also called an arrhythmia or dysrhythmia) is any of a group of conditions in which the electrical activity of the heart is irregular. During this state, the heartbeat may be too fast (over 100 beats per minute) or too slow (less than 60 beats per minute) and may be regular or irregular. A heartbeat that is too fast is called tachycardia, and a heartbeat that is too slow is called bradycardia. Although many arrhythmias are not life-threatening, it is worth noting that some can cause cardiac arrest in extreme cases.

An abnormal heartbeat is most commonly induced under the influence of moderate dosages of a stimulants and depressants compounds, such as cocaine,[1] methamphetamine, and GABAergics. While stimulants tend to increase a person's heart rate, depressants tend to decrease it. Combining the two can often result in dangerously irregular heartbeats.

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

... further results

Experience reports

Anecdotal reports which describe this effect within our experience index include:

See also

References

  1. ↑ O’Leary, Michael E, and Jules C Hancox. “Role of Voltage-Gated Sodium, Potassium and Calcium Channels in the Development of Cocaine-Associated Cardiac Arrhythmias.” British Journal of Clinical Pharmacology 69.5 (2010): 427–442. PMC. Web. 27 June 2017.
Retrieved from "https://psy.st/index.php?title=Abnormal_heartbeat&oldid=142661"