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Antihistamine: Difference between revisions

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>Unity
Expanded.
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Divided antihistamines into the first and second generations
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==Examples==
==Examples==
Antihistamines are found throughout organic chemistry and include psychoactive and anti-allergenic compounds.
Antihistamines are found throughout organic chemistry and include psychoactive and anti-allergenic compounds.
 
=== First-generation antihistamines ===
*[[Cyclizine]]
*[[Cyclizine]]
*[[Diphenhydramine]]
*[[Diphenhydramine]]
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*[[Hydroxyzine]]
*[[Hydroxyzine]]
*[[Meclozine]]
*[[Meclozine]]
*[[Promethazine]]
=== Second-generation antihistamines ===
*[[Cetirizine]]
*[[Loratadine]]
=== Other ===
*[[Mirtazapine]]
*[[Mirtazapine]]
*[[Promethazine]]
*[[Quetiapine]]
*[[Quetiapine]]



Revision as of 15:51, 15 October 2019

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

The chemical structure of histamine

Antihistamines are a class of substances that inhibit the action of histamine. Antihistamines are commonly used to relieve allergies and to promote sleep.[1] Recreationally, very high doses can be used to induce delirium and achieve a hallucinogenic effect in which the user sees and hears fully-formed, extremely convincing hallucinations. However, this experience is typically considered highly unpleasant by most users.

The toxicity of recreational antihistamine use is poorly understood, although there is some evidence that abuse may cause cognitive deficits and other health issues.[citation needed]

Pharmacology

This pharmacology section is incomplete.

You can help by adding to it.

Most antihistamines act as inverse agonists on histamine receptors, meaning they inhibit the action of histamine by preventing it from binding to them. They may also inhibit the enzymatic activity of histidine decarboxylase which catalyzes the transformation of histidine into histamine.[citation needed]

Examples

Antihistamines are found throughout organic chemistry and include psychoactive and anti-allergenic compounds.

First-generation antihistamines

Second-generation antihistamines

Other

See also

Literature

References

  1. Sicherer, Scott H. M.D., Understanding and Managing Your Child's Food Allergy. Baltimore: The Johns Hopkins University Press, 2006 ISBN 0-8018-8492-6.