Antipsychotic: Difference between revisions
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'''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>{{cite book | vauthors=((Finkel, R.)), ((Clark, M. A.)), ((Cubeddu, L. X.)) | date= 2009 | title=Pharmacology | publisher=Lippincott Williams & Wilkins | isbn=9780781771559}}</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[Delusions|delusions]], [[External hallucinations|hallucinations]], or [[thought disorganization|disordered thought]]), particularly in [[wikipedia:schizophrenia|schizophrenia]] and [[wikipedia:bipolar disorder|bipolar disorder]]. | '''Antipsychotics''' (also known as '''neuroleptics''' or '''major tranquilizers''')<ref>{{cite book | vauthors=((Finkel, R.)), ((Clark, M. A.)), ((Cubeddu, L. X.)) | date= 2009 | title=Pharmacology | publisher=Lippincott Williams & Wilkins | isbn=9780781771559}}</ref> are a class of psychiatric medication primarily used to manage [[psychosis]] (including [[Delusions|delusions]], [[External hallucinations|hallucinations]], or [[thought disorganization|disordered thought]]), particularly in [[wikipedia:schizophrenia|schizophrenia]] and [[wikipedia:bipolar disorder|bipolar disorder]]. | ||
Revision as of 16:06, 13 February 2023
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Different antipsychotics reduce the intensity of trips in different ways. |
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are known to reduce the intensity of trips unequally
Antipsychotics (also known as neuroleptics or major tranquilizers)[1] are a class of psychiatric medication primarily used to manage psychosis (including delusions, hallucinations, or disordered thought), particularly in schizophrenia and bipolar disorder.
First generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second generation drugs, called atypical antipsychotics, have been developed more recently. The first atypical antipsychotic, clozapine, was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's dopamine pathways; atypicals tend to act on serotonin receptors as well.
Notable and relatively common adverse effects of antipsychotics include extrapyramidal symptoms (which involve motor control and are very serious), hyperprolactinaemia (primarily in typicals), weight gain and metabolic abnormalities (mostly in atypicals).[2]
Examples
First-generation (typical) antipsychotics
- Aceperone
- Acepromazine
- Acetophenazine
- Azaperone
- Amitriptyline
- Benperidol
- Bromperidol
- Chlorpromazine
- Chlorprothixene
- Clopenthixol
- Cyamemazine
- Dixyrazine
- Droperidol
- Flupentixol
- Fluphenazine
- Fluspirilene
- Haloperidol
- Levomepromazine
- Loxapine
- Mesoridazine (Serentil)
- Moperone
- Penfluridol
- Perazine
- Pericyazine
- Perphenazine
- Pimozide
- Pipamperone
- Pipotiazine
- Prochlorperazine
- Promazine
- Promethazine
- Prothipendyl
- Sulphride
- Thioproperazine
- Thioridazine
- Thiothixene
- Timiperone
- Trifluoperazine
- Triflupromazine
Second-generation (atypical) antipsychotics
- Amisulpride
- Aripiprazole
- Aripiprazole lauroxil (Aristada)
- Brexpiprazole
- Cariprazine
- Clozapine
- Iloperidone
- Lurasidone
- Lumateperone
- Melperone
- Nemonapride
- Olanzapine
- Paliperidone
- Perospirone
- Quetiapine
- Remoxipride
- Risperidone
- Sultopride
- Ziprasidone
- Zuclopenthixol
Third-generation antipsychotics
- Phenylpiperazines/quinolinones
- Aripiprazole (Abilify)
- Aripiprazole lauroxil (Abilify Maintena)
- Brexpiprazole
- Cariprazine
- Benzisoxazoles/benzisothiazoles
- Lurasidone (Latuda)
See also
External links
References
- ↑ Finkel, R., Clark, M. A., Cubeddu, L. X. (2009). Pharmacology. Lippincott Williams & Wilkins. ISBN 9780781771559.
- ↑ Frankenburg, F. R.; Dunayevich, E.; Albucher, R. C.; Talavera, F. "Schizophrenia". emedicine.medscape.com. Retrieved 2013-10-02.