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* Tryptophan ** 5-HTP → serotonin ** Melatonin
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Any '''precursor''' (sometimes even '''starting baterial''') are chemical compounda that, after synthesizing (sometimes multiple times) results in one or more pharmacologically active substances on interest.
Any '''drug''' or '''chemical''' that, after synthesizing results in one or more pharmacologically active substances of interest is a precursor.<ref>C. G. Wermuth, C. R. Ganellin, P. Lindberg, L. A. Mitscher; Ganellin; Lindberg; Mitscher (1998). "Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)". Pure and Applied Chemistry. 70 (5): 1129. https://doi.org/10.1351/pac199870051129</ref> Precursors can be psychoactive compounds or non-psychoactive compounds. A list of some precursors can be found below.
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Precursors can be psychoactive compounds or non-psychoactive compounds.


==List of drug precursors==
==List of drug precursors==


===List of synthetic drug precursors===
===List of synthetic drug precursors===
* [[2,5-DMA]] → [[DOB]], [[DOC]], [[DOI]], [[DON]]
 
* [https://en.wikipedia.org/wiki/2,5-Dimethoxybenzaldehyde 2,5-dimethoxybenzaldehyde] for [[2,5-DMA]], [[2C-H]]
*[[2,5-DMA]] → [[DOB]], [[DOC]], [[DOI]], [[DON]]
* [[2C-B]] → [[25B-NBOMe]], [[2C-C]] → [[25CB-NBOMe]], [[2C-D]] → [[25D-NBOMe]], etc
*[https://en.wikipedia.org/wiki/2,5-Dimethoxybenzaldehyde 2,5-dimethoxybenzaldehyde] for [[2,5-DMA]], [[2C-H]]
* [[2C-H]] → [[2C-B]], [[2C-C]], [[2C-D]], etc
*[[2C-B]] → [[25B-NBOMe]], [[2C-C]] → [[25CB-NBOMe]], [[2C-D]] → [[25D-NBOMe]], etc
* [https://en.wikipedia.org/wiki/Anethole Anethole] → [[PMA]], [[PMMA]]
*[[2C-H]] → [[2C-B]], [[2C-C]], [[2C-D]], etc
* [[DOB]] → [[DOEF]]
*[[5-meo-trypamine]] → [[5-meo-DMT]]
* [https://en.wikipedia.org/wiki/Elemicin Elemicin] → [[mescaline]]
*[https://en.wikipedia.org/wiki/Anethole Anethole] → [[PMA]], [[PMMA]]
* [[Ephedrine]] → [[methamphetamine]]
*[[DOB]] → [[DOEF]]
* [[Ergotamine]] → [[LSD]]
*[https://en.wikipedia.org/wiki/Elemicin Elemicin] → [[mescaline]]
* [[LSA]] → [[LSD]]
*[[Ephedrine]] → [[methamphetamine]]
* [[Morphine]] → [[codeine]]
*[[Ergotamine]] → [[LSD]]
* [https://en.wikipedia.org/wiki/Phenyl-2-nitropropene P2NP] → [[amphetamine]]
*[[GABA]] → [[GBL]] → [[GHB]]
* [[Pseudoephedrine]] → [[methamphetamine]]
*[[LSA]] → [[LSD]]
* [https://en.wikipedia.org/wiki/Safrole Safrole]/[https://en.wikipedia.org/wiki/Isosafrole isosafrole] → [[MDMA]]
*[[Morphine]] → [[codeine]]
* [[Thebaine]] → [[codeine]], and [[oxycodone]]
*[https://en.wikipedia.org/wiki/Phenyl-2-nitropropene P2NP] → [[amphetamine]]
* [[nor-LSD]] → [[AL-LAD]], [[ETH-LAD]], [[LSD]], probably more
*[[Pseudoephedrine]] → [[methamphetamine]]
* [[Norepinephrine]] → [[epinephrine]] (adrenaline)
*[https://en.wikipedia.org/wiki/Safrole Safrole]/[https://en.wikipedia.org/wiki/Isosafrole isosafrole] → [[MDMA]]
* [[Phenylalanine]] →  [[phenethylamine]]
*[[Thebaine]] → [[codeine]], and [[oxycodone]]
* [[Picamilon]] → [[GABA]]
*[[nor-LSD]] → [[AL-LAD]], [[ETH-LAD]], [[LSD]], probably more
* [[Tyramine]] → [[dopamine]], N-Methyltyramine (NMT), and octopamine
*[[Norepinephrine]] → [[epinephrine]] (adrenaline)
* [[Tyrosine]] → [[L-DOPA]], and [[tyramine]]
*[[Phenylalanine]] →  [[phenethylamine]]
* [[Tryptophan]] → [[5-HTP]], and [[melatonin]]
*[[Picamilon]] → [[GABA]]
*[[Piperazine]] → [[BZP]]
*[[Tyramine]] → [[dopamine]], N-Methyltyramine (NMT), and octopamine
*[[Tyrosine]] → [[L-DOPA]], and [[tyramine]]
*[[Tryptophan]] → [[5-HTP]], and [[melatonin]]


===List of GMO drug precursors===
===List of GMO drug precursors===
* GMO yeast -> Psilocybin.<ref>{{cite web |last1=Denmark |first1=Technical University of |title=Psychedelic compound from magic mushrooms produced in yeast |url=https://phys.org/news/2020-04-psychedelic-compound-magic-mushrooms-yeast.html |website=phys.org |language=en}}</ref><!-- link found at https://octarinebio.com/ -->
See also: [[Psychoactive substances, and precursor chemicals, produced by GMOs]]
* GMO Tequila bacteria -> THC<ref>{{cite web |title=Yeast produce low-cost, high-quality cannabinoids |url=https://www.sciencedaily.com/releases/2019/02/190227131838.htm |website=ScienceDaily |language=en}}</ref><ref>{{cite web |title=German scientists use gene-edited Tequila bacteria to produce cannabinoids |url=https://www.thedrinksbusiness.com/2019/03/german-scientists-use-gene-edited-tequila-bacteria-to-produce-cannabinoids/ |website=The Drinks Business |date=28 March 2019}}</ref>
 
* GMO Baker’s Yeast -> Lysergic acid (LSD precursor)<ref>{{cite web |title=LSD Precursor From Baker’s Yeast |url=https://uvachemistry.com/2011/06/29/lsd-precursor-from-bakers-yeast/ |website=Sciences In the Mural Of Life |language=en |date=29 June 2011}}</ref>
{{Precursor chemicals produced by GMOs}}
* GMO E. coli -> Thebaine (morphine precursor)<ref>{{cite web |title=Genetically modified E. coli pump out morphine precursor: Bacteria yield 300 times more opiates than yeast |url=https://www.sciencedaily.com/releases/2016/02/160225101103.htm |website=ScienceDaily |language=en}}</ref>


==List of neurotransmitter precursors in humans==
==List of neurotransmitter precursors in humans==
* Phenylalanine, tyrosine → epinephrine
{{List of neurotransmitter precursors in humans}}
* Dopamine → epinephrine, norepinephrine
* Tyrosine → L-DOPA → dopamine
* [[Tryptophan]]
** [[5-HTP]] → serotonin
** [[Melatonin]]


==See also==
==See also==
* [[List of prodrugs]]
*[[List of human endogenous compounds]]
*[[List of prodrugs]]


==External links==
==External links==
* [https://en.wikipedia.org/wiki/Catecholamine Catecholamine (Wikipedia)]
 
* [https://en.wikipedia.org/wiki/Neurotransmitter Neurotransmitter (Wikipedia)]
*[https://en.wikipedia.org/wiki/Catecholamine Catecholamine (Wikipedia)]
* [https://en.wikipedia.org/wiki/Precursor_chemicals Precursor chemicals (Wikipedia)]
*[https://en.wikipedia.org/wiki/Neurotransmitter Neurotransmitter (Wikipedia)]
* [https://en.wikipedia.org/wiki/Precursor_(chemistry) Precursor (chemistry) (Wikipedia)]
*[https://en.wikipedia.org/wiki/Precursor_chemicals Precursor chemicals (Wikipedia)]
*[https://en.wikipedia.org/wiki/Precursor_(chemistry) Precursor (chemistry) (Wikipedia)]


[[Category:Precursor]]
[[Category:Precursor]]
[[Category:Substance-related lists]]
[[Category:Substance-related lists]]
<references />
{{#set:Featured=true}}

Latest revision as of 01:17, 12 May 2024

Any drug or chemical that, after synthesizing results in one or more pharmacologically active substances of interest is a precursor.[1] Precursors can be psychoactive compounds or non-psychoactive compounds. A list of some precursors can be found below.

List of drug precursors

List of synthetic drug precursors

List of GMO drug precursors

See also: Psychoactive substances, and precursor chemicals, produced by GMOs

  • Lysergic acid (LSD precursor)
    • GMO yeast: Baker’s Yeast[2]
  • Thebaine (morphine precursor)
    • GMO bacteria: E. coli[3]

List of neurotransmitter precursors in humans

  • Phenylalanine, tyrosine → epinephrine
  • Dopamine → epinephrine, norepinephrine
  • Tryptophan
  • Tyrosine → L-DOPA → dopamine
  • Tyramine → dopamine, N-Methyltyramine (NMT), and octopamine

See also

  1. ↑ C. G. Wermuth, C. R. Ganellin, P. Lindberg, L. A. Mitscher; Ganellin; Lindberg; Mitscher (1998). "Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)". Pure and Applied Chemistry. 70 (5): 1129. https://doi.org/10.1351/pac199870051129
  2. ↑ "Harvesting baker's yeast for aging-related therapeutics". ScienceDaily. 
  3. ↑ "Genetically modified E. coli pump out morphine precursor: Bacteria yield 300 times more opiates than yeast". ScienceDaily. 


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