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N,N-Dipropyltryptamine (DPT, also known as "The Light") is a psychedelic drug belonging to the tryptamine family, first reported in 1973. DPT is an intense synthetic hallucinogenic drug. DPT is the primary sacrament for "Temple of the True Inner Light" a Christian off shoot organization that believes in psychedelics and primarily DPT as the true flesh of God.
{{SummarySheet}}
{{SubstanceBox/DPT}}
'''N,N-Dipropyltryptamine''' (also known as '''Dipropyltryptamine''', '''DPT''', and '''"The Light"''') is a lesser-known [[psychoactive class::psychedelic]] substance of the [[chemical class::tryptamine]] class. It is closely related to [[DMT]] and is reported to be uniquely similar in its hallucinogenic intensity, albeit with a moderately longer duration and greater unpredictability relative to DMT and other psychedelic tryptamines.
DPT is most commonly consumed via insuffalation or Intramuscular injection. Some report the experience of insuffalation being very painful, which with the rapidness of onset, does not give the user much time to acclimate themselves to the effects as they come on strongly.
DPT was first synthesized in 1950.<ref>{{cite journal|last1=Li|first1=J. X.|last2=Rice|first2=K.|last3=France|first3=C. P.|year=2007|title=Behavioral effects of dipropyltryptamine in rats: evidence for 5-HT1A and 5-HT2A agonist activity|journal=Behavioural Pharmacology|issn=0955-8810|eissn=1473-5849|oclc=22170289|volume=18|issue=4|pages=283-288|doi=10.1097/FBP.0b013e3281f19ca0|pmid=17551320}}</ref> Human use was first reported in 1973, where it was researched in low doses as an adjunct to therapy for alcoholism.<ref>{{cite journal|last1=Grof|first1=S.|last2=Soskin|first2=R. A.|last3=Richards|first3=W. A.|last4=Kurland|first4=A. A.|title=DPT as an Adjunct in Psychotherapy of Alcoholics|year=1973|journal=International Pharmacopsychiatry|issn=0020-8272|oclc=1753673|doi=10.1159/000467979|pmid=4150711|volume=8|issue=1|pages=104-115}}</ref> It has also been researched in high doses to induce peak experiences for terminal cancer patients.<ref>{{cite journal|last1=Richards|first1=W. A.|last2=Rhead|first2=J. C.|last3=Dileo|first3=F. B.|last4=Yensen|first4=R.|last5=Kurland|first5=A. A.|title=The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients|year=1977|volume=9|issue=1|journal=Journal of Psychedelic Drugs|pages=1-10|issn=0022-393X|oclc=7565359|doi=10.1080/02791072.1977.10472020}}</ref> It has gained some notoriety for its adoption as the primary sacrament for the "Temple of the True Inner Light" in the United States, a Christian off-shoot organization who believe in the ritual use of [[psychedelics]] and refer to them as "the true flesh of God."<ref>{{cite web|title=Temple of the True Inner Light|access-date=January 9, 2020|url=http://psychede.tripod.com/}}</ref>
DPT is commonly consumed via [[insufflation]] or [[orally]]. Many report the experience of insufflation to be very congestive and painful which, with the rapidness of onset, does not give the user much time to acclimate themselves to its powerful effects. It can also be administered [[intramuscular|intramuscularly]] or via [[vaporization]] after conversion to the freebase form. Smoking the freebase is reported to be the preferred route used by the "Temple of True Inner Light". More experienced members ingest a DPT tea. {{citation needed}}
Very little data exists about the pharmacological properties, metabolism, and toxicity of DPT, and it has relatively little history of human usage. It has long been available on the [[research chemicals]] market as a legal, grey-market alternative to [[DMT]], and commercially distributed through online vendors. Many reports also suggest that this substance may be overly difficult to use safely for those who are not already very experienced with [[hallucinogens]]. It is highly advised to approach this powerful [[psychedelic]] substance with the proper amount of precaution and [[Responsible drug use#Hallucinogens|harm reduction practices]] when using it.
==Chemistry==
==Chemistry==
[[File:SubstitutedTryptamine.png|thumb|294px|right|General formula of a tryptamine molecule.]]
DPT, or N,N-dipropyltryptamine, is a synthetic indole molecule of the [[tryptamine]] class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R<sub>3</sub> to an amino group via an ethyl side chain. DPT contains two propyl groups carbon chains bound to the terminal amine R<sub>N</sub> of its tryptamine backbone.
DPT has a number of substituted analogs such as [[4-HO-DPT]] or [[4-AcO-DPT]].
==Pharmacology==
==Pharmacology==
{{Main|Serotonergic psychedelic}}
{{pharmacology}}
DMT's [[psychedelic]] effects are believed to come from its efficacy at the [[Serotonin#The 5-HT System|5-HT<sub>2A</sub> receptor]] as a [[Agonist#Agonists|partial agonist]]. However, the role of these interactions and how they result in the [[psychedelic]] experience continues to remain elusive.
{{Further|Serotonergic psychedelic}}
Studies on rodents have found that the effectiveness with which a selective 5-HT<sub>2A</sub> receptor antagonist blocks the behavioral actions of this compound strongly suggest that the 5-HT<sub>2A</sub> receptor is an important site of action for DPT, but the modulatory actions of a 5-HT<sub>1A</sub> receptor antagonist also imply a 5-HT<sub>1A</sub>-mediated component to the actions of DPT.<ref>{{cite journal | vauthors=((Fantegrossi, W.)), ((Reissig, C.)), ((Katz, E.)), ((Yarosh, H.)), ((Rice, K.)), ((Winter, J.)) | journal=Pharmacology Biochemistry and Behavior | title=Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): Possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents | volume=88 | issue=3 | pages=358–365 | date= January 2008 | url=https://linkinghub.elsevier.com/retrieve/pii/S0091305707002894 | issn=00913057 | doi=10.1016/j.pbb.2007.09.007}}</ref> The role of these interactions and how they result in the [[psychedelic]] experience remains the subject of ongoing scientific investigation.
==Subjective effects==
==Subjective effects==
The effects listed below are based upon the [[subjective effects index]] and personal experiences of [[PsychonautWiki]] [[PsychonautWiki#Contributors|contributors]]. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.
Relative to psychedelic tryptamines like DMT, DPT is often reported to be similar in its [[hallucinogenic]] intensity, albeit with a moderately longer duration and more challenging effects. DPT experiences are often described as a "bizarre", "unsettling", and "darker" version of DMT experiences. DPT is reported to be more sensual and physical than DMT and other psychedelics with a corresponding amount of adverse physical effects.
===Physical effects===
The physical effects of DPT can often be jarring. At light to moderate doses there is often a slight sense of anesthetization and relaxation. As the dose increases, perceptions of heart rate increase, body tremors, and loss of muscle control are often reported.
===Cognitive effects===
DMT in its smokeable form is perhaps the least psychologically intoxicating [[psychedelic]]. It is due to this lack of mental intoxication that many people describe DMT not as something which feels not like a drug induced trip but a genuine experience that is actually happening to them. It's worth noting that many people report that DMT is extremely clear headed in its style and contains less personal insight in comparison to orally active [[psychedelics]] such as [[ayahuasca]], [[LSD]] and [[psilocin]] due to its short acting nature.
It contains a limited amount of typical cognitive effects. The most prominent of these typical effects generally include:
*'''[[Cognitive effects: Enhancement of current mind state|Enhancement of current mind state]]'''
At light to moderate doses, users often report a slight sense of anaesthetization and relaxation. As the dose increases, hyper-awareness of one's heart rate and breathing increases and body tremors and loss of muscle control are often reported. The effects of DPT can range from strong euphoria and sensuality to nausea, panic, and intense states dysphoria even within the same experience.
*'''[[Cognitive effects: Removal of cultural filter|Removal of cultural filter]]'''
*'''[[Cognitive effects: Feelings of fascination, importance and awe|Feelings of fascination, importance and awe]]'''
DMT presents a full and complete array of possible visual enhancements which generally include:
*'''[[Effect::Spontaneous bodily sensations]]''' - The "body high" of DPT is generally more prominent to that of the better known [[DMT]]. There is often the sensation of limbs feeling disconnected from the body, a force pinning the body to the surface on which it lay and body tremors which can often make the user feel aware of but not in control of their body.
**'''[[Effect::Physical euphoria]]'''
*'''[[Effect::Physical autonomy]]'''
*'''[[Effect::Changes in felt bodily form]]'''
*'''[[Effect::Changes in felt gravity]]''' - At higher doses, physical feelings of moving through spaces at quick speeds or being completely pinned down are common.
*'''[[Effect::Abnormal heartbeat]]'''
*'''[[Effect::Increased blood pressure]]'''
*'''[[Effect::Motor control loss]]'''
*'''[[Effect::Muscle contractions]]'''
*'''[[Effect::Nausea]]'''
*'''[[Effect::Headaches]]'''
*'''[[Effect::Dehydration]]'''
*'''[[Effect::Excessive yawning]]'''
*'''[[Effect::Pupil dilation]]'''
*'''[[Effect::Increased libido]]''' - This effect appears to occur with more regularity and intensity than other psychedelic tryptamines.
As for visual distortions and alterations, effects experienced are detailed below:
*'''[[Effect::Drifting]]''' ''([[Drifting#Melting|melting]], [[Drifting#Breathing|breathing]], [[Drifting#Morphing|morphing]] and [[Drifting#Flowing|flowing]])''
*'''[[Effect::After images]]'''
*'''[[Visual effects: Drifting|Drifting]]''' ''([[Visual effects: Drifting#Melting|Melting]], [[Visual effects: Drifting#Breathing|Breathing]], [[Visual effects: Drifting#Morphing|Morphing]] and [[Visual effects: Drifting#Flowing|Flowing]])'' - In comparison to other [[psychedelics]] this effect can be described as highly detailed, slow and smooth in motion and static in their appearance.
*'''[[Effect::Colour replacement]]'''
*'''[[Visual effects: Tracers|Tracers]]'''
*'''[[Effect::Colour shifting]]'''
*'''[[Visual effects: After images|After images]]'''
The visual geometry that is present throughout this trip can be described as more similar in appearance to that of [[Psilocin]] than [[LSD]]. It can be comprehensively described through its [[Visual_effects:_Geometry#Variations|variations]] as intricate in complexity, abstract in form, equally organic and digital in feel, structured in organization, brightly lit, multicoloured in scheme, glossy in shading, equal in sharp and soft edges, large in size, fast in speed, smooth in motion, equal in rounded and angular corners, immersive in depth and consistent in its intensity. At higher dosages it is significantly more likely to result in states of [[Level 8B]] visual geometry over [[Level 8A]].
The geometry present with smokeable DMT is often considered to be the most profoundly intricate and complex set of visual geometry found within the entirety of the [[psychedelic]] experience. In comparison to orally active DMT ([[ayahuasca]]) it is significantly more digital in appearance and contain a colour scheme which is similar to [[LSD]] but a structured style that is closer to high dose [[Psilocin]].
====[[Effect::Geometry]]====
DPT visual geometry can be described through its variations as intricate in complexity, both abstract and concrete in form, more digital than organic in feel, choppy and only loosely structured in organization, brightly lit, multicolored in scheme, sharp in its edges, fast in speed, simultaneously smooth and glitching in motion, immersive in depth, and consistent in intensity. At higher doses, it is more likely to result in states of [[Effect::8A Geometry|level 8A geometry]] over level 8B.
====Hallucinatory states====
====Hallucinatory states====
DMT produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of any other commonly used psychedelic. These effects include:
DPT produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of any other commonly used psychedelic barring [[DMT]] and [[ibogaine]]. These effects include:
*'''[[Visual effects: Internal hallucinations|Internal hallucinations]]''' (''[[Visual effects: Autonomous entities|Autonomous entities]]'', ''[[Visual effects: Settings, sceneries, and landscapes|Settings, sceneries, and landscapes]]'', ''[[Visual effects: Alterations in perspective|Alterations in perspective]]'' and ''[[Visual effects: Scenarios and plots|Scenarios and plots]]'') - DMT produces high level internal hallucinations at appropriate dosages perhaps more consistently than that of any other [[psychedelic]]. They are more common within dark environments and can be comprehensively described through their [[Visual_effects:_Internal_hallucinations#Variations|variations]] as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, geometry based in style and almost exclusively of a religious, spiritual, mystical or transcendental nature in their overall theme.
===Auditory effects===
*'''[[Effect::Transformations]]'''
The auditory effects of DMT are common in their occurrence and exhibit a full range of effects which commonly include:
*'''[[Effect::Machinescapes]]''' - These are reported to be more common with [[DPT]] than with [[DMT]], which lends to its common description as feeling more "industrial" and futuristic, while [[DMT]] visuals can often be described as "ancient" or "earthy" in feel.
*'''[[Effect::Internal hallucination]]''' (''[[effect::autonomous entities]]''; ''[[effect::settings, sceneries, and landscapes]]''; ''[[effect::perspective hallucinations]]'' and ''[[effect::scenarios and plots]]'') - As with [[DMT]], DPT produces high level internal hallucinations at appropriate doses more consistently than most other [[psychedelics]]. They are more common within dark environments and can be comprehensively described through their [[Internal_hallucinations#Variations|variations]] as lucid in believability, interactive in style, new experiences in content, non-autonomous in controllability, geometry-based in style and almost exclusively of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental narrative in their overall theme, with a tendency towards chaotic disorganization and incoherence.
*'''[[Effect::External hallucination]]''' (''[[effect::autonomous entities]]''; ''[[effect::settings, sceneries, and landscapes]]''; ''[[effect::perspective hallucinations]]'' and ''[[effect::scenarios and plots]]'') - These are more common within dark environments and can be comprehensively described through their [[External_hallucinations#Variations|variations]] as lucid in believability, interactive in style, new experiences in content, non-autonomous in controllability, geometry-based in style and typically of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental narrative in their overall theme, with a tendency towards chaotic disorganization and incoherence.
The first step of a DMT trip is the come up that leads onto breaking through. This is something that seems to have at least a few different ways of presenting itself to the user as they start to smoke DMT.
*'''[[Effect::Déjà vu]]'''
*'''[[Effect::Emotionality enhancement]]'''
*'''[[Effect::Feelings of impending doom]]'''
**'''[[Effect::Catharsis]]'''
**'''[[Effect::Rejuvenation]]'''
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Increased sense of humor]]'''
**'''[[Effect::Laughter fits]]'''
*'''[[Effect::Novelty enhancement]]'''
*'''[[Effect::Immersion enhancement]]'''
*'''[[Effect::Personal meaning enhancement]]'''
*'''[[Effect::Memory suppression]]'''
**'''[[Effect::Ego death]]'''
*'''[[Effect::Confusion]]'''
*'''[[Effect::Language suppression]]'''
*'''[[Effect::Personal bias suppression]]'''
*'''[[Effect::Simultaneous emotions]]'''
*'''[[Effect::Spatial disorientation]]'''
*'''[[Effect::Autonomous voice communication]]'''
*'''[[Effect::Multiple thought streams]]'''
*'''[[Effect::Thought disorganization]]'''
*'''[[Effect::Thought loops]]'''
*'''[[Effect::Time distortion]]'''
*'''[[Effect::Wakefulness]]'''
The first thing that a person notices is an extremely distinct set of visual enhancements and most notably an increase in [[Visual effects: Increased visual acuity|visual acuity]] and [[Visual effects: Enhancement of colour|colour intensity]].
}}
{{effects/multisensory|
*'''[[Effect::Synaesthesia]]''' - In its fullest manifestation, this is a very rare and non-reproducible effect. Increasing the dosage can increase the likelihood of this occurring, but seems to only be a prominent part of the experience among those who are already predisposed to synaesthetic states.
This is followed by a sudden onset of high level 3 [[Visual effects: Geometry (psychedelic)|geometry]], the [[Physical effects: Spontaneous tactile sensations|body high]] and the feeling of your body being pleasantly tugged in all directions at once from the inside.
}}
{{effects/transpersonal|
Many reports indicate that while [[DPT]] possesses the raw [[hallucinogenic]] power to induce transpersonal states traditionally associated with "classical psychedelics", it does so in a significantly less consistent fashion due to the utter bizarreness and oft-noted "sinister", chaotic, or "forceful" undertones that can be present throughout the experience. What insights it can lead the user to typically occur during the aftermath and integration phase that follows, which shares some qualities of a typical near-death experience.
This is often accompanied by a soft crackling sound and an extended tone that quickly increases in volume and pitch proportionally as the visual effects increase. This sound becomes all enveloping abruptly ends as one of a few different "take off" options are experienced.
*'''[[Effect::Spirituality enhancement]]'''
*'''[[Effect::Existential self-realization]]'''
*'''[[Effect::Perception of predeterminism]]'''
*'''[[Effect::Perception of eternalism]]'''
*'''[[Effect::Perceived exposure to inner mechanics of consciousness]]'''
*'''[[Effect::Unity and interconnectedness]]'''
These include, but are certainly not limited to:
}}
}}
*Feelings of suddenly being pushed through and onto the other side of a membrane,
===Experience reports===
*The external environment splitting in two down the middle leaving a gaping infinite chasm filled with incredibly fast moving visuals as you separate from your body shooting directly into it at light speed
Anecdotal reports which describe the effects of this compound within our [[experience index]] include:
*Increasingly intense [[Visual effects: Geometry (psychedelic)|geometry]] simply becoming so all enveloping that absolutely nothing of the room is left any more.
Almost immediately after a person has smoked enough DMT to have "taken off", they often find themselves spending a brief amount of time in what is described to feel like a [[psychedelic]] "waiting room" or perhaps a "loading screen". This can take any form but generally appears in the shape of a tunnel or space comprised of fast moving simply becoming so all enveloping that absolutely nothing of the room is left any more. that lasts approximately 10 – 20 seconds and feels distinctively different from the main bulk of the trip.
{{toxicity}}
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
The toxicity and long-term health effects of recreational DPT do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because DPT is a [[research chemical]] with very little history of human usage. There has been one death associated with the use DPT and seizures, but the dose is unknown.<ref>{{Citation | vauthors=((Tribune, B. D. S.)) | title=Carver County teen’s death puts spotlight on ease of purchasing synthetic drugs online | url=https://www.startribune.com/carver-county-teen-s-death-puts-spotlight-on-ease-of-purchasing-synthetic-drugs-online/330344661/}}</ref>
This distinctive feeling has led many people to speculate that it’s during this moment that the trip ahead of you is being generated and planned out.
Anecdotal reports from those who have taken DPT suggests that negative health effects are not likely to occur from simply trying it by itself at low to moderate doses and using it sparingly (although nothing can be guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.
The waiting room starts off quickly but immediately begins to slow down and form into the third and most important stage.
It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.
=====The other side=====
===Tolerance and addiction potential===
DPT is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. As with most psychedelics, it is reported to be self-limiting.
Once the waiting period is over and the trip has been generated the user will feel that they have broken through onto the other side. It is here where literally anything can happen to you, but despite this most trips seem to follow some extremely common archetypes and plots that happen almost universally across people who have tried DMT.
Tolerance to the effects of DPT has been shown to not be built in animal models.<ref>{{cite journal|last1=Smith|first1=D. A.|last2=Bailey|first2=J. M.|last3=Williams|first3=D.|last4=Fantegrossi|first4=W. E.|title=Tolerance and Cross-Tolerance to Head Twitch Behavior Elicited by Phenethylamine- and Tryptamine-Derived Hallucinogens in Mice|year=2014|journal=Journal of Pharmacology and Experimental Therapeutics|volume=351|issue=2|pages=485-491|doi=10.1124/jpet.114.219337|pmid= 25271256|pmc=4309922|issn=0022-3565|eissn=1521-0103|oclc=1606914}}</ref> However, it has been reported to be able to build slightly relative to [[DMT]], although still to an insignificant degree compared to most psychedelics.
These generally consist of visiting in an alternate reality that feels so real it seems to be better defined than real life. Usually, this is with a single or multiple external autonomous entities in front of your line of sight. These entities appear to have been waiting for the user's arrival and usually seem completely unsurprised by the user's sudden appearance into their dimension. They immediately begin to greet and welcome them with open arms, giving off a sense that they are deeply concerned with what they have to show you in the short amount of time that they have before one begins to come down.
===Dangerous interactions===
{{DangerousInteractions/Intro}}
At this point, it is pretty common for the user (unless they are very experienced) to be completely overwhelmed by the nature of what is happening to them despite feeling completely sober mentally, often screaming and shouting in amazement as the entities encourage the user to stay calm, not to give into astonishment and to simply try to pay attention to what is happening. It’s here that they start to communicate with the user using a variety of different methods such as directly manipulating what they can see and view, by telepathically beaming information into their thoughts, by using a visual language comprised of pure linguistic meaning and mathematics or any combination of the above. It’s through these that they teach their message or show the user what they want to show them.
*'''[[Tramadol]]''' - Tramadol lowers the seizure threshold<ref>{{cite journal|last1=Talaie|first1=H.|last2=Panahandeh|first2=R.|last3=Fayaznouri|first3=M. R.|last4=Asadi|first4=Z.|last5=Abdollahi|first5=M.|title=Dose-independent occurrence of seizure with tramadol|year=2009|journal=Journal of Medical Toxicology|volume=5|issue=2|pages=63-67|doi=10.1007/BF03161089|issn=1556-9039|eissn=1937-6995|oclc=163567183|pmid=19415589|pmc=3550327}}</ref> and LSD also has the potential to induce seizures in susceptible individuals. and [[psychedelics]] may act as triggers for seizures, particularly in those who are predisposed to them.{{citation needed}}
*'''[[Stimulants]]''' - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable [[anxiety]], [[Panic attacks|panic]], [[thought loops]] and [[paranoia]]. This interaction may cause elevated risk of psychosis.{{citation needed}}
*'''[https://en.wikipedia.org/wiki/Lithium_(medication) Lithium]''' - Lithium is often used as treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its [[Glutamate|glutaminergic]] and [[GABA|GABAergic]] effects.{{citation needed}}
This message is often something personal to the user or something that only applies to the logic of the universe in which it was taught in, making it impossible to integrate and apply it into everyday life.
==Legal status==
These entities often appear to be all-knowing and although they can take any form, commonly experienced entities are present. These generally include ''bodiless super intelligent humanoids, aliens, elves, insectoids, giant spheres, beings of light, plants and complex robotic machines''.
*'''Germany''': DPT is controlled under the NpSG (''New Psychoactive Substances Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/anlage.html|title=Anlage NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]|access-date=December 10, 2019|language=de}}</ref> as of July 18, 2019.<ref>{{cite web|url=http://www.bgbl.de/xaver/bgbl/start.xav?startbk=Bundesanzeiger_BGBl&jumpTo=bgbl119s1083.pdf|title=Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes|publisher=Bundesanzeiger Verlag|work=Bundesgesetzblatt Jahrgang 2019 Teil I Nr. 27|pages=1083-1094|publication-date=July 17, 2019|access-date=January 1, 2020|language=de}}</ref> Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/__4.html|title=§ 4 NpSG|publisher=Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]|access-date=December 10, 2019|language=de}}</ref>
*'''Latvia''': DPT is a Schedule I controlled substance.<ref>{{cite web|url=http://likumi.lv/doc.php?id=121086|title=Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem|publisher=VSIA Latvijas Vēstnesis|access-date=January 1, 2020|publication-date=November 10, 2005|language=lv}}</ref>
*'''New Zealand''': DPT is an analogue of DMT, therefore it is a Class C controlled substance in New Zealand.<ref>{{cite web|title=Schedule 1 Class A controlled drugs|url=http://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html#DLM436576|work="Reprint as at 13 August 2019: Misuse of Drugs Act 1975"|access-date=January 7, 2020|publisher=Parliamentary Counsel Office}}</ref>
*'''Sweden''': Following its sale as a [[designer drug]], DPT was made illegal in Sweden on January 26, 2016.<ref>{{cite web|url=https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2016/januari/31-nya-substanser-klassas-som-narkotika-eller-halsofarlig-vara|title=31 nya substanser klassas som narkotika eller hälsofarlig vara|publisher=Folkhälsomyndigheten [Public Health Agency of Sweden]|access-date=January 1, 2020|publication-date=January 26, 2016|language=sv}}</ref>
*'''Switzerland''': DPT is a controlled substance specifically named under Verzeichnis E.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref>
*'''United Kingdom''': DPT is a Class A controlled substance in the United Kingdom as a result of the tryptamine catch-all clause.<ref>{{cite web|title=Part I: Class A Drugs|url=http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I|work="Misuse of Drugs Act 1971"|access-date=January 7, 2020|publisher=UK Government}}</ref>
*'''United States''': DPT is unscheduled in most of the United States. However, some states prohibited DPT, making it illegal to buy, sell, or possess:
**'''Florida''': DPT is a Schedule I controlled substance.<ref>{{cite web|url=http://leg.state.fl.us/statutes/index.cfm?App_mode=Display_Statute&URL=0800-0899/0893/0893.html|title=Title XLVI: Chapter 893: Drug Abuse Prevention And Control|work=The 2019 Florida Statutes|access-date=January 10, 2020|publisher=The Florida Legislature}}</ref>
**'''Maine''': DPT is a Schedule X controlled substance.<ref>http://legislature.maine.gov/statutes/17-a/title17-Asec1102.html</ref>
**'''Oklahoma''': DPT is a Schedule I controlled substance.<ref>{{cite web|archive-url=https://web.archive.org/web/20190709113340/http://www.oscn.net/applications/oscn/DeliverDocument.asp?CiteID=98866|archive-date=July 9, 2019|url=http://www.oscn.net/applications/oscn/DeliverDocument.asp?CiteID=98866|title=Section 2-204 - Schedule I|work=Oklahoma Statutes Citationized|date=January 11, 2019|access-date=January 10, 2020|publisher=Oklahoma Judicial Center}}</ref>
Just as quickly as the DMT hits, after several minutes it begins to leave the user at the final stage of the trip.
==See also==
=====Coming down=====
*[[Responsible use]]
The final stage is experienced as the sensation of being pulled further and further away from the scenario in which one was placed as the entities often wave goodbye and encourage one to come back when you next get the chance.
*[[Research chemical]]
*[[Psychedelics]]
*[[Tryptamines]]
*[[DMT]]
*[[DET]]
Once this is over the user immediately find themself back in reality with strong level 4 - 5 visual [[Visual effects: geometry (psychedelic)|geometry]]. This is accompanied by an incredible sense of [[Physical effects: Euphoria|euphoria]] and awe which washes over every part of their mind and body. The moderate to mild [[Visual effects: geometry (psychedelic)|geometry]] stays for a further 10 – 15 minutes before disappearing completely, leaving a strong body high that stays for up to an hour. This afterglow feels like a warm fuzziness and leaves behind a sense of well being and mental clarity that can last up to weeks after a good trip.
DMT is not known to cause brain damage, and has extremely low toxicity relative to dose. Similar to other [[psychedelic]] drugs, there are relatively few physical side effects associated with DMT exposure. Various studies have shown that in reasonable doses in a careful context, it presents no negative cognitive, psychiatric or toxic physical consequences of any sort.
===Lethal Dosage===
*Soskin, R.A., Grof, S., & Richards, W.A. (1973). Low doses of Dipropyltryptamine in psychotherapy. Archives of General Psychiatry, 28 6, 817-21.
The median lethal dose or dosage at which 50% of participants die (LD50) of DMT for human beings has never been reached in any setting.
*Richards, W. A., Rhead, J. C., DiLeo, F. B., Yensen, R., & Kurland, A. A. (1977). The peak experience variable in DPT-assisted psychotherapy with cancer patients. Journal of Psychedelic Drugs, 9(1), 1-10. http://dx.doi.org/10.1080/02791072.1977.10472020
*Grof, S., Soskin, R. A., Richards, W. A., & Kurland, A. A. (1972). DPT as an adjunct in psychotherapy of alcoholics. International Pharmacopsychiatry, 8(1), 104-115. PMID: 4150711
*Li, J., Rice, K.C., & France, C.P. (2007). Behavioral effects of dipropyltryptamine in rats: evidence for 5-HT1A and 5-HT2A agonist activity. Behavioural Pharmacology, 18 4, 283-8.
In mice, the median lethal dose (LD50) of DMT when administered intravenously is 110 milligrams per kilogram (mg/kg). This means that approximately 6600 milligrams (6.6 grams) of pure DMT would be required for a 60-kilogram (130 lb) person to reach the 110 mg/kg LD50 value of mice. This is roughly 110 times the commonly used dosage of 60mg.
==References==
<references />
===Tolerance and Addiction Potential===
[[Category:Substance]]
There is no tolerance with DMT usage, meaning that it can be used multiple times in a day without the effects diminishing. Due to the mind-altering psychedelic effects, most users show no addiction to DMT and use often decreases with time.
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.
DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
N,N-Dipropyltryptamine (also known as Dipropyltryptamine, DPT, and "The Light") is a lesser-known psychedelic substance of the tryptamine class. It is closely related to DMT and is reported to be uniquely similar in its hallucinogenic intensity, albeit with a moderately longer duration and greater unpredictability relative to DMT and other psychedelic tryptamines.
DPT was first synthesized in 1950.[1] Human use was first reported in 1973, where it was researched in low doses as an adjunct to therapy for alcoholism.[2] It has also been researched in high doses to induce peak experiences for terminal cancer patients.[3] It has gained some notoriety for its adoption as the primary sacrament for the "Temple of the True Inner Light" in the United States, a Christian off-shoot organization who believe in the ritual use of psychedelics and refer to them as "the true flesh of God."[4]
DPT is commonly consumed via insufflation or orally. Many report the experience of insufflation to be very congestive and painful which, with the rapidness of onset, does not give the user much time to acclimate themselves to its powerful effects. It can also be administered intramuscularly or via vaporization after conversion to the freebase form. Smoking the freebase is reported to be the preferred route used by the "Temple of True Inner Light". More experienced members ingest a DPT tea. [citation needed]
Very little data exists about the pharmacological properties, metabolism, and toxicity of DPT, and it has relatively little history of human usage. It has long been available on the research chemicals market as a legal, grey-market alternative to DMT, and commercially distributed through online vendors. Many reports also suggest that this substance may be overly difficult to use safely for those who are not already very experienced with hallucinogens. It is highly advised to approach this powerful psychedelic substance with the proper amount of precaution and harm reduction practices when using it.
DPT, or N,N-dipropyltryptamine, is a synthetic indole molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. DPT contains two propyl groups carbon chains bound to the terminal amine RN of its tryptamine backbone.
DPT has a number of substituted analogs such as 4-HO-DPT or 4-AcO-DPT.
Studies on rodents have found that the effectiveness with which a selective 5-HT2A receptor antagonist blocks the behavioral actions of this compound strongly suggest that the 5-HT2A receptor is an important site of action for DPT, but the modulatory actions of a 5-HT1A receptor antagonist also imply a 5-HT1A-mediated component to the actions of DPT.[5] The role of these interactions and how they result in the psychedelic experience remains the subject of ongoing scientific investigation.
Subjective effects
Relative to psychedelic tryptamines like DMT, DPT is often reported to be similar in its hallucinogenic intensity, albeit with a moderately longer duration and more challenging effects. DPT experiences are often described as a "bizarre", "unsettling", and "darker" version of DMT experiences. DPT is reported to be more sensual and physical than DMT and other psychedelics with a corresponding amount of adverse physical effects.
At light to moderate doses, users often report a slight sense of anaesthetization and relaxation. As the dose increases, hyper-awareness of one's heart rate and breathing increases and body tremors and loss of muscle control are often reported. The effects of DPT can range from strong euphoria and sensuality to nausea, panic, and intense states dysphoria even within the same experience.
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects
Spontaneous bodily sensations - The "body high" of DPT is generally more prominent to that of the better known DMT. There is often the sensation of limbs feeling disconnected from the body, a force pinning the body to the surface on which it lay and body tremors which can often make the user feel aware of but not in control of their body.
DPT visual geometry can be described through its variations as intricate in complexity, both abstract and concrete in form, more digital than organic in feel, choppy and only loosely structured in organization, brightly lit, multicolored in scheme, sharp in its edges, fast in speed, simultaneously smooth and glitching in motion, immersive in depth, and consistent in intensity. At higher doses, it is more likely to result in states of level 8A geometry over level 8B.
Hallucinatory states
DPT produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of any other commonly used psychedelic barring DMT and ibogaine. These effects include:
Machinescapes - These are reported to be more common with DPT than with DMT, which lends to its common description as feeling more "industrial" and futuristic, while DMT visuals can often be described as "ancient" or "earthy" in feel.
Internal hallucination (autonomous entities; settings, sceneries, and landscapes; perspective hallucinations and scenarios and plots) - As with DMT, DPT produces high level internal hallucinations at appropriate doses more consistently than most other psychedelics. They are more common within dark environments and can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, non-autonomous in controllability, geometry-based in style and almost exclusively of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental narrative in their overall theme, with a tendency towards chaotic disorganization and incoherence.
External hallucination (autonomous entities; settings, sceneries, and landscapes; perspective hallucinations and scenarios and plots) - These are more common within dark environments and can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, non-autonomous in controllability, geometry-based in style and typically of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental narrative in their overall theme, with a tendency towards chaotic disorganization and incoherence.
Synaesthesia - In its fullest manifestation, this is a very rare and non-reproducible effect. Increasing the dosage can increase the likelihood of this occurring, but seems to only be a prominent part of the experience among those who are already predisposed to synaesthetic states.
Many reports indicate that while DPT possesses the raw hallucinogenic power to induce transpersonal states traditionally associated with "classical psychedelics", it does so in a significantly less consistent fashion due to the utter bizarreness and oft-noted "sinister", chaotic, or "forceful" undertones that can be present throughout the experience. What insights it can lead the user to typically occur during the aftermath and integration phase that follows, which shares some qualities of a typical near-death experience.
This toxicity and harm potential section is a stub.
As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.
The toxicity and long-term health effects of recreational DPT do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because DPT is a research chemical with very little history of human usage. There has been one death associated with the use DPT and seizures, but the dose is unknown.[6]
Anecdotal reports from those who have taken DPT suggests that negative health effects are not likely to occur from simply trying it by itself at low to moderate doses and using it sparingly (although nothing can be guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.
DPT is not habit-forming and the desire to use it can actually decrease with use. As with most psychedelics, it is reported to be self-limiting.
Tolerance to the effects of DPT has been shown to not be built in animal models.[7] However, it has been reported to be able to build slightly relative to DMT, although still to an insignificant degree compared to most psychedelics.
Dangerous interactions
Warning:Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).
Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.
Tramadol - Tramadol lowers the seizure threshold[8] and LSD also has the potential to induce seizures in susceptible individuals. and psychedelics may act as triggers for seizures, particularly in those who are predisposed to them.[citation needed]
Stimulants - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable anxiety, panic, thought loops and paranoia. This interaction may cause elevated risk of psychosis.[citation needed]
Lithium - Lithium is often used as treatment for bipolar disorder. It may possibly cause elevated risk of seizures and psychosis due to its glutaminergic and GABAergic effects.[citation needed]
Legal status
Germany: DPT is controlled under the NpSG (New Psychoactive Substances Act)[9] as of July 18, 2019.[10] Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.[11]
Latvia: DPT is a Schedule I controlled substance.[12]
New Zealand: DPT is an analogue of DMT, therefore it is a Class C controlled substance in New Zealand.[13]
Sweden: Following its sale as a designer drug, DPT was made illegal in Sweden on January 26, 2016.[14]
Switzerland: DPT is a controlled substance specifically named under Verzeichnis E.[15]
United Kingdom: DPT is a Class A controlled substance in the United Kingdom as a result of the tryptamine catch-all clause.[16]
United States: DPT is unscheduled in most of the United States. However, some states prohibited DPT, making it illegal to buy, sell, or possess:
Florida: DPT is a Schedule I controlled substance.[17]
Maine: DPT is a Schedule X controlled substance.[18]
Oklahoma: DPT is a Schedule I controlled substance.[19]
Soskin, R.A., Grof, S., & Richards, W.A. (1973). Low doses of Dipropyltryptamine in psychotherapy. Archives of General Psychiatry, 28 6, 817-21.
Richards, W. A., Rhead, J. C., DiLeo, F. B., Yensen, R., & Kurland, A. A. (1977). The peak experience variable in DPT-assisted psychotherapy with cancer patients. Journal of Psychedelic Drugs, 9(1), 1-10. http://dx.doi.org/10.1080/02791072.1977.10472020
Grof, S., Soskin, R. A., Richards, W. A., & Kurland, A. A. (1972). DPT as an adjunct in psychotherapy of alcoholics. International Pharmacopsychiatry, 8(1), 104-115. PMID: 4150711
Li, J., Rice, K.C., & France, C.P. (2007). Behavioral effects of dipropyltryptamine in rats: evidence for 5-HT1A and 5-HT2A agonist activity. Behavioural Pharmacology, 18 4, 283-8.
↑Grof, S.; Soskin, R. A.; Richards, W. A.; Kurland, A. A. (1973). "DPT as an Adjunct in Psychotherapy of Alcoholics". International Pharmacopsychiatry. 8 (1): 104–115. doi:10.1159/000467979. ISSN0020-8272. OCLC1753673. PMID4150711.
↑Richards, W. A.; Rhead, J. C.; Dileo, F. B.; Yensen, R.; Kurland, A. A. (1977). "The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients". Journal of Psychedelic Drugs. 9 (1): 1–10. doi:10.1080/02791072.1977.10472020. ISSN0022-393X. OCLC7565359.
↑"Anlage NpSG" (in Deutsch). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
↑"§ 4 NpSG" (in Deutsch). Bundesministerium der Justiz und für Verbraucherschutz [Federal Ministry of Justice and Consumer Protection]. Retrieved December 10, 2019.
↑"Schedule 1 Class A controlled drugs". "Reprint as at 13 August 2019: Misuse of Drugs Act 1975". Parliamentary Counsel Office. Retrieved January 7, 2020.
↑"Section 2-204 - Schedule I". Oklahoma Statutes Citationized. Oklahoma Judicial Center. January 11, 2019. Archived from the original on July 9, 2019. Retrieved January 10, 2020.
. PMID 25271256.