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Template:DangerousInteractions/SerotoninSyndrome: Difference between revisions

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Combinations with the following substances can increase the amount of [[serotonin]] in the brain to dangerous, possibly fatal, levels.
Combinations with the following substances can cause dangerously high [[serotonin]] levels. [[Serotonin syndrome]] requires immediate medical attention and can be fatal if left untreated.
*'''[[DangerousInteraction::MAOIs]]''' such as '''[[syrian rue]]''', '''[[banisteriopsis caapi]]''', '''[[2C-T-2]]''', '''[[2C-T-7]]''', '''[[αMT]]''', and some [[antidepressant]]s<ref>Gillman, P. K. (2005). Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. British Journal of Anaesthesia, 95(4), 434-441. https://doi.org/10.1093/bja/aei210</ref>
*'''[[DangerousInteraction::MAOIs]]''' - {{#switch:{{{self}}}
*'''[[DangerousInteraction::Serotonin releasers]]''' such as '''[[MDMA]]''', '''[[4-FA]]''', '''[[methylone]]''' and '''[[αMT]]'''
|Syrian_rue=Such as [[banisteriopsis caapi]], phenelzine, selegiline, and moclobemide.
*'''[[DangerousInteraction::Selective serotonin re-uptake inhibitors]] (SSRIs)'''
|Banisteriopsis_caapi=Such as [[syrian rue]], phenelzine, selegiline, and moclobemide.
*'''[[DangerousInteraction::Serotonin-norepinephrine reuptake inhibitors]] (SNRIs)''' such as '''[[tramadol]]''' and '''[[DXM]]'''
|Such as [[banisteriopsis caapi]], [[syrian rue]], phenelzine, selegiline, and moclobemide.}}<ref>{{cite journal|last1=Gillman|first1=P. K.|year=2005|title=Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity|journal=British Journal of Anaesthesia|volume=95|issue=4|url=https://bjanaesthesia.org/article/S0007-0912(17)34956-5/fulltext|pages=434-441|doi=10.1093/bja/aei210|pmid=16051647|doi-access=free|issn=0007-0912|eissn=1471-6771|oclc=01537271}}</ref>
*'''[[DangerousInteraction::5-HTP]]'''
*'''[[DangerousInteraction::Serotonin releasers]]''' - {{#switch:{{{self}}}
|MDMA=Such as [[4-FA]], [[methamphetamine]], [[methylone]] and [[αMT]].
|4-FA=Such as [[MDMA]], [[methamphetamine]], [[methylone]] and [[αMT]].
|Methamphetamine=Such as [[MDMA]], [[4-FA]], [[methylone]] and [[αMT]].
|Methylone=Such as [[MDMA]], [[4-FA]], [[methamphetamine]] and [[αMT]].
|AMT=Such as [[MDMA]], [[4-FA]], [[methamphetamine]] and [[methylone]].
|Such as [[MDMA]], [[4-FA]], [[methamphetamine]], [[methylone]] and [[αMT]].}}
*'''[[DangerousInteraction::SSRIs]]''' - Such as citalopram and sertraline
*'''[[Wikipedia:SNRIs|[[DangerousInteraction::SNRIs]]]]''' - Such as {{#ifeq:{{{self}}}|Tramadol|venlafaxine|[[tramadol]] and venlafaxine}}
{{#ifeq:{{{self}}}|5-HTP||*'''[[DangerousInteraction::5-HTP]]'''}}

Latest revision as of 21:00, 15 September 2022

Combinations with the following substances can cause dangerously high serotonin levels. Serotonin syndrome requires immediate medical attention and can be fatal if left untreated.

  1. ↑ Gillman, P. K. (2005). "Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity". British Journal of Anaesthesia. 95 (4): 434–441. doi:10.1093/bja/aei210 Freely accessible. eISSN 1471-6771. ISSN 0007-0912. OCLC 01537271. PMID 16051647. 
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