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F-Phenibut: Revision history

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31 January 2025

18 November 2023

  • curprev 20:0420:04, 18 November 2023 >Emo Entity m 12,633 bytes 0 capitalized the first letter of "analysis suppression" in the list of subjective effects
  • curprev 20:0420:04, 18 November 2023 >Emo Entity m 12,633 bytes 0 capitalized the first letter of "analysis suppression" in the list of subjective effects
  • curprev 20:0420:04, 18 November 2023 >Emo Entity m 12,633 bytes 0 capitalized the first letter of "analysis suppression" in the list of subjective effects
  • curprev 20:0420:04, 18 November 2023 >Emo Entity m 12,633 bytes +1,253 capitalized the first letter of "analysis suppression" in the list of subjective effects

15 September 2023

2 September 2023

26 August 2023

31 January 2023

29 November 2022

17 August 2022

  • curprev 07:5107:51, 17 August 2022 >Winch 12,368 bytes 0 F-Phenibut = stronger GABA B agonist, weaker Calcium Channel Blocker. Thus it has a better tolerance profile than Phenibut. F-Phenibut lasts half as long as Phenibut, meaning the difference is not high enough to say that compulsive redosing is more pronounced with the fluorinated version. It's also worth mentioning this characteristic is more specific to dopaminergic and opioidergic agents because of their immediate stimulation of the reward pathway unlike GABAergic and Ion channels depressants.
  • curprev 07:5107:51, 17 August 2022 >Winch 12,368 bytes 0 F-Phenibut = stronger GABA B agonist, weaker Calcium Channel Blocker. Thus it has a better tolerance profile than Phenibut. F-Phenibut lasts half as long as Phenibut, meaning the difference is not high enough to say that compulsive redosing is more pronounced with the fluorinated version. It's also worth mentioning this characteristic is more specific to dopaminergic and opioidergic agents because of their immediate stimulation of the reward pathway unlike GABAergic and Ion channels depressants.
  • curprev 07:5107:51, 17 August 2022 >Winch 12,368 bytes −133 F-Phenibut = stronger GABA B agonist, weaker Calcium Channel Blocker. Thus it has a better tolerance profile than Phenibut. F-Phenibut lasts half as long as Phenibut, meaning the difference is not high enough to say that compulsive redosing is more pronounced with the fluorinated version. It's also worth mentioning this characteristic is more specific to dopaminergic and opioidergic agents because of their immediate stimulation of the reward pathway unlike GABAergic and Ion channels depressants.
  • curprev 07:3807:38, 17 August 2022 >Winch 12,501 bytes 0 No edit summary
  • curprev 07:3807:38, 17 August 2022 >Winch 12,501 bytes 0 No edit summary
  • curprev 07:3807:38, 17 August 2022 >Winch 12,501 bytes +133 No edit summary
  • curprev 07:3507:35, 17 August 2022 >Winch 12,368 bytes 0 No edit summary
  • curprev 07:3507:35, 17 August 2022 >Winch 12,368 bytes 0 No edit summary
  • curprev 07:3507:35, 17 August 2022 >Winch 12,368 bytes −133 No edit summary
  • curprev 07:2907:29, 17 August 2022 >Winch 12,501 bytes 0 F-Phenibut lasts half as long as Phenibut and is a weaker calcium channel blocker but more potent GABA B agonist. For this reason, it has a better tolerance profile than Phenibut. It is not short lasting enough for "compulsive redosing": someone that ends up compulsively redosing F-Phenibut every 5 hours would do the same with Phenibut every 10 hours. To conclude, compulsive redosing is the most relevant with dopaminergic agents and the long lasting Methamphetamine is still highly addictive.
  • curprev 07:2907:29, 17 August 2022 >Winch 12,501 bytes 0 F-Phenibut lasts half as long as Phenibut and is a weaker calcium channel blocker but more potent GABA B agonist. For this reason, it has a better tolerance profile than Phenibut. It is not short lasting enough for "compulsive redosing": someone that ends up compulsively redosing F-Phenibut every 5 hours would do the same with Phenibut every 10 hours. To conclude, compulsive redosing is the most relevant with dopaminergic agents and the long lasting Methamphetamine is still highly addictive.
  • curprev 07:2907:29, 17 August 2022 >Winch 12,501 bytes +25 F-Phenibut lasts half as long as Phenibut and is a weaker calcium channel blocker but more potent GABA B agonist. For this reason, it has a better tolerance profile than Phenibut. It is not short lasting enough for "compulsive redosing": someone that ends up compulsively redosing F-Phenibut every 5 hours would do the same with Phenibut every 10 hours. To conclude, compulsive redosing is the most relevant with dopaminergic agents and the long lasting Methamphetamine is still highly addictive.

16 August 2022

  • curprev 09:0209:02, 16 August 2022 >Winch 12,476 bytes 0 F-Phenibut is unlikely to be more addictive than Phenibut, because it's a less potent Calcium Channels Blocker and more potent GABA B agonist. Calcium channels blockade is the main reason behind the dependance profile of classic Phenibut. F-Phenibut finds its way between Phenibut and Baclofen.
  • curprev 09:0209:02, 16 August 2022 >Winch 12,476 bytes 0 F-Phenibut is unlikely to be more addictive than Phenibut, because it's a less potent Calcium Channels Blocker and more potent GABA B agonist. Calcium channels blockade is the main reason behind the dependance profile of classic Phenibut. F-Phenibut finds its way between Phenibut and Baclofen.
  • curprev 09:0209:02, 16 August 2022 >Winch 12,476 bytes −133 F-Phenibut is unlikely to be more addictive than Phenibut, because it's a less potent Calcium Channels Blocker and more potent GABA B agonist. Calcium channels blockade is the main reason behind the dependance profile of classic Phenibut. F-Phenibut finds its way between Phenibut and Baclofen.

27 July 2022

8 February 2022

22 March 2021

28 December 2020

  • curprev 20:1920:19, 28 December 2020 >ResearchSlore 11,320 bytes 0 F-Phenibut is a potent GABA-B agonist. I added this information along with a source.
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