This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Tactile suppression
Tactile suppression can be described as sensations of anaesthesia and a simple decrease of sensation or general numbness across the body. At higher levels, this can eventually increase to the point where physical sensations have been completely blocked and the body is fully anaesthetized.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 3-Cl-PCP
- 3-HO-PCE
- 3-HO-PCP
- 3-MeO-PCE
- 3-MeO-PCMo
- 3-MeO-PCP
- 4-MeO-PCP
- Alcohol
- Benzydamine
- Datura
- Deschloroketamine
- Dextromethorphan
- Diphenhydramine
- Diphenidine
- Ephenidine
- GBL
- HXE
- Ketamine
- MXiPr
- Memantine
- Methoxetamine
- Methoxphenidine
- Myristicin
- N-Ethylhexedrone
- Nitrous
- O-PCE
- PCE
- PCP
- Rolicyclidine
Experience reports
Anecdotal reports which describe this effect within our experience index include:
- Experience: 300mg DXM (Oral) - Brink of the third
- Experience:17mg 3-MeO-PCP & Cannabis oil - Terrifying confusion
- Experience:260 mg Ketamine (insufflated) - Lost in Paisley
- Experience:7500mg - Analysis of gabapentin
- Experience:MXE: 37.5 mg - Calm and Cloudy Bliss
- Experience:Nitrous oxide (approx. 50 puffs) - ~50 puffs nitrous oxide
- Experience:Unknown Dose DOC (Insufflated) - Overdosing and Terifying Ego Death
- Experience:~150mg MDA(oral) - a case of mistaken identity